Retinal Photoreceptor Functions Are Compromised in Patients With Resistance to Thyroid Hormone Syndrome (RTHβ) | Zendy

Irene Campi | Zendy; Gabriella Cammarata | Zendy; Stefania Bianchi Marzoli | Zendy; Paolo BeckPeccoz | Zendy; Diletta Santarsiero | Zendy; Davide Dazzi | Zendy; Alessandra Bottari de Castello | Zendy; Elena Taroni | Zendy; Francesco Viola | Zendy; Caterina Mian | Zendy; Sara WatutantrigeFernando | Zendy; Carla Pelusi | Zendy; Marina Muzza | Zendy; Maria Antonia Maffini | Zendy; Luca Persani | Zendy

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Retinal Photoreceptor Functions Are Compromised in Patients With Resistance to Thyroid Hormone Syndrome (RTHβ)

Author(s) -

Irene Campi,

Gabriella Cammarata,

Stefania Bianchi Marzoli,

Paolo BeckPeccoz,

Diletta Santarsiero,

Davide Dazzi,

Alessandra Bottari de Castello,

Elena Taroni,

Francesco Viola,

Caterina Mian,

Sara WatutantrigeFernando,

Carla Pelusi,

Marina Muzza,

Maria Antonia Maffini,

Luca Persani

Publication year - 2017

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2016-3671

Subject(s) - retinal , electroretinography , erg , retina , endocrinology , ophthalmology , medicine , thyroid , retinal degeneration , biology , neuroscience

In animal models, disruption of thyroid hormone (TH) receptor-β (TRβ) reduces the long/medium wavelength (L/M) and increases the short-wavelength (S) cones. Retinal photoreceptor (RP) functions are unknown in patients with resistance to TH syndrome (RTHβ) with dominant-negative TRβ mutations.

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