Chronic Intranasal Insulin Does Not Affect Hepatic Lipids but Lowers Circulating BCAAs in Healthy Male Subjects | Zendy

Thomas Scherer | Zendy; Peter Wolf | Zendy; Sabina Smajis | Zendy; Melania Gaggini | Zendy; Martina Häckl | Zendy; Amalia Gastaldelli | Zendy; Peter Klimek | Zendy; Elisa Einwallner | Zendy; Rodrig Marculescu | Zendy; Anton Luger | Zendy; Clemens Fürnsinn | Zendy; Siegfried Trattnig | Zendy; Christoph Buettner | Zendy; Martin Krššák | Zendy; Michael Krebs | Zendy

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Chronic Intranasal Insulin Does Not Affect Hepatic Lipids but Lowers Circulating BCAAs in Healthy Male Subjects

Author(s) -

Thomas Scherer,

Peter Wolf,

Sabina Smajis,

Melania Gaggini,

Martina Häckl,

Amalia Gastaldelli,

Peter Klimek,

Elisa Einwallner,

Rodrig Marculescu,

Anton Luger,

Clemens Fürnsinn,

Siegfried Trattnig,

Christoph Buettner,

Martin Krššák,

Michael Krebs

Publication year - 2017

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2016-3623

Subject(s) - nasal administration , affect (linguistics) , medicine , endocrinology , insulin , immunology , psychology , communication

Nonalcoholic fatty liver disease and elevated circulating branched-chain amino acids (BCAAs) are common characteristics of obesity and type 2 diabetes. In rodents, brain insulin signaling controls both hepatic triglyceride secretion and BCAA catabolism. Whether brain insulin signaling controls similar metabolic pathways in humans is unknown.

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