Thyroid Status and Mortality in a Prospective Hemodialysis Cohort
Author(s) -
Connie M. Rhee,
Amy S. You,
Danh V. Nguyen,
Steven M. Brunelli,
Matthew J. Budoff,
Elani Streja,
Tracy Nakata,
Csaba P. Kövesdy,
Gregory A. Brent,
Kamyar KalantarZadeh
Publication year - 2017
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2016-3616
Subject(s) - medicine , hemodialysis , hazard ratio , prospective cohort study , dialysis , proportional hazards model , population , confidence interval , thyroid disease , risk of mortality , cohort study , thyroid , endocrinology , environmental health
Compared with the general population, hemodialysis patients have a substantially higher risk of hypothyroidism, as defined by an elevated serum thyrotropin (TSH) level, and cardiovascular mortality. Whereas an elevated TSH is associated with cardiovascular disease and death in the general population, associations among dialysis patients have been inconsistent.
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