Open AccessObesity Modulates Inflammation and Lipid Metabolism Oocyte Gene Expression: A Single-Cell Transcriptome Perspective
Author(s) -
Meghan L. Ruebel,
Matthew Cotter,
Clark R. Sims,
Dean M. Moutos,
Thomas M. Badger,
Mario A. Cleves,
Kartik Shankar,
Aline Andres
Publication year - 2017
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2016-3524
Subject(s) - endocrinology , medicine , oocyte , insulin resistance , transcriptome , biology , leptin , gene expression , andrology , insulin , obesity , gene , genetics , embryo
It is hypothesized that obesity adversely affects the ovarian environment, which can disrupt oocyte maturation and embryonic development.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom