Reduced Transforming Growth Factor-β Activity in the Endometrium of Women With Heavy Menstrual Bleeding
Author(s) -
Jacqueline A. Maybin,
Lyndsey Boswell,
Vicky J. Young,
W. Colin Duncan,
Hilary Critchley
Publication year - 2017
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2016-3437
Subject(s) - immunostaining , endometrium , menstrual cycle , stromal cell , endocrinology , transforming growth factor , medicine , follicular phase , immunohistochemistry , andrology , hormone
Heavy menstrual bleeding (HMB) is common and incapacitating. Aberrant menstrual endometrial repair may result in HMB. The transforming growth factor (TGF)-β superfamily contributes to tissue repair, but its role in HMB is unknown.
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