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Polycystic ovary syndrome (PCOS) is associated with increased risk of endometrial cancer. This is usually explained by chronic anovulation and deficient progesterone activity. However, the role of progesterone receptors (PRs) in endometrial proliferation is unclear.

Progesterone Receptors and Proliferation of the Endometrium in Obese Women With Polycystic Ovary Syndrome—A Lifestyle Intervention Study