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Fibrogenesis Imperfecta Ossium and Response to Human Growth Hormone: A Potential Therapy
Author(s) -
Sanjay Kumar Bhadada,
Vandana Dhiman,
Soham Mukherjee,
Sameer Aggarwal,
Amanjit Bal,
Suja Sukumar,
Ashwani Sood,
Dinesh C Sharma,
Niranjan Khandelwal,
Anil Bhansali,
Wim Van Hul,
Sudhaker D. Rao
Publication year - 2017
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2016-3055
Subject(s) - medicine , osteogenesis imperfecta , osteomalacia , bone remodeling , bone disease , parathyroid hormone , endocrinology , biopsy , bone density , pathology , osteoporosis , calcium
Fibrogenesis imperfecta ossium (FIO) is a rare bone disease manifested by generalized bone pain, fragility fractures, progressive disability, and extensive mineralization defect seen in bone biopsy specimens. The pathogenesis of the disease is unknown and currently there is no effective treatment.

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