Thyroid Signaling, Insulin Resistance, and 2 Diabetes Mellitus: A Mendelian Randomization Study
Author(s) -
Maxime M. Bos,
Roelof A.J. Smit,
Stella Trompet,
Diana van Heemst,
Raymond Noordam
Publication year - 2017
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2016-2816
Subject(s) - mendelian randomization , insulin resistance , type 2 diabetes , medicine , genome wide association study , endocrinology , odds ratio , diabetes mellitus , genetic association , glycemic , insulin , genetics , biology , single nucleotide polymorphism , genotype , genetic variants , gene
Increasing evidence suggests an association between thyroid-stimulating hormone (TSH), free thyroxine (fT4), and deiodinases with insulin resistance and type 2 diabetes mellitus (T2D).
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