The Desmopressin Test Predicts Better Than Basal Cortisol the Long-Term Surgical Outcome of Cushing's Disease | Zendy

Dimitra A. Vassiliadi | Zendy; Maria Balomenaki | Zendy; Athina Asimakopoulou | Zendy; Efi Botoula | Zendy; Marinella Tzanela | Zendy; S. Tsagarakis | Zendy

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The Desmopressin Test Predicts Better Than Basal Cortisol the Long-Term Surgical Outcome of Cushing's Disease

Author(s) -

Dimitra A. Vassiliadi,

Maria Balomenaki,

Athina Asimakopoulou,

Efi Botoula,

Marinella Tzanela,

S. Tsagarakis

Publication year - 2016

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2016-2799

Subject(s) - cushing's disease , medicine , basal (medicine) , desmopressin , hazard ratio , confidence interval , endocrinology , receiver operating characteristic , transsphenoidal surgery , gastroenterology , cortisol awakening response , retrospective cohort study , hydrocortisone , disease , adenoma , pituitary adenoma , insulin

Cushing's disease (CD) has a significant relapse rate after successful transsphenoidal surgery (TSS). Many CD patients respond aberrantly to the desmopressin test (DT). Disappearance of this response after surgery may suggest complete removal of abnormal corticotrophs and a lower possibility of recurrence.

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