Low DHEAS: A Sensitive and Specific Test for Detection of Subclinical Hypercortisolism in Adrenal Incidentalomas
Author(s) -
Michael Conall Dennedy,
Anand K. Annamalai,
Olivia Prankerd Smith,
Natalie Freeman,
Kuhan Vengopal,
Johann Graggaber,
Olympia Koulouri,
Andrew S. Powlson,
Ashley Shaw,
David Halsall,
Mark Gurnell
Publication year - 2016
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2016-2718
Subject(s) - endocrinology , medicine , dexamethasone suppression test , metanephrines , dehydroepiandrosterone sulfate , aldosterone , subclinical infection , dexamethasone , basal (medicine) , hydrocortisone , adrenal insufficiency , pheochromocytoma , androgen , hormone , insulin
Subclinical hypercortisolism (SH) occurs in 5% to 30% of adrenal incidentalomas (AIs). Common screening tests for adrenocorticotropin-independent hypercortisolism have substantial false-positive rates, mandating further time and resource-intensive investigations.
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