Urinary Citrate, an Index of Acid-Base Status, Predicts Bone Strength in Youths and Fracture Risk in Adult Females | Zendy

Jonas Esche | Zendy; Simone A. Johner | Zendy; Lijie Shi | Zendy; Eckhard Schönaü | Zendy; Thomas Remer | Zendy

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Urinary Citrate, an Index of Acid-Base Status, Predicts Bone Strength in Youths and Fracture Risk in Adult Females

Author(s) -

Jonas Esche,

Simone A. Johner,

Lijie Shi,

Eckhard Schönaü,

Thomas Remer

Publication year - 2016

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2016-2677

Subject(s) - medicine , urinary system , biomarker , urine , excretion , quantitative computed tomography , bone density , endocrinology , physiology , urology , osteoporosis , chemistry , biochemistry

Diet can impact on bone strength via metabolic shifts in acid-base status. In contrast to the strongly diet-dependent biomarker urinary potential renal acid load (uPRAL), the amount of renally excreted citrate integrates nutritional and systemic influences on acid-base homeostasis with high citrate indicating prevailing alkalization.

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