Open AccessAdipocyte Browning and Higher Mitochondrial Function in Periadrenal But Not SC Fat in Pheochromocytoma
Author(s) -
Laurent Vergnes,
Graeme Davies,
Jason Y. Lin,
Michael W. Yeh,
Masha J. Livhits,
Avital Harari,
Michael Symonds,
Harold S. Sacks,
Karen Reue
Publication year - 2016
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2016-2670
Subject(s) - browning , adipocyte , endocrinology , medicine , adipose tissue , chemistry , biology , biochemistry
Patients with pheochromocytoma (pheo) show presence of multilocular adipocytes that express uncoupling protein 1 within periadrenal (pADR) and omental (OME) fat depots. It has been hypothesized that this is due to adrenergic stimulation by catecholamines produced by the pheo tumors.
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