Open AccessLINE1 CpG-DNA Hypomethylation in Granulosa Cells and Blood Leukocytes Is Associated With PCOS and Related Traits
Author(s) -
Pooja Sagvekar,
Vijay Mangoli,
Sadhana Desai,
Anushree Patil,
Srabani Mukherjee
Publication year - 2017
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2016-2645
Subject(s) - dna methylation , cpg site , biology , medicine , endocrinology , genetics , gene , gene expression
Altered global DNA methylation is indicative of epigenomic instability concerning chronic diseases. Investigating its incidence and association with polycystic ovary syndrome (PCOS) is essential to understand the etiopathogenesis of this disorder.
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