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Cord Blood Adipokines and Lipids and Adolescent Nonalcoholic Fatty Liver Disease
Author(s) -
Joy Simpson,
Andrew Smith,
Abigail Fraser,
Naveed Sattar,
Mark Callaway,
Robert S. Lindsay,
Debbie A. Lawlor,
Scott M. Nelson
Publication year - 2016
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2016-2604
Subject(s) - adiponectin , nonalcoholic fatty liver disease , offspring , medicine , body mass index , endocrinology , birth weight , adipokine , leptin , cord blood , pregnancy , fatty liver , physiology , adipose tissue , obesity , biology , insulin resistance , disease , genetics
Maternal adiposity in pregnancy is associated with offspring adiposity and metabolic dysfunction postnatally, including greater risk of nonalcoholic fatty liver disease (NAFLD). Recent genetic analyses suggest a causal effect of greater maternal body mass index on offspring birth weight and ponderal index, but the relative roles of the environment in utero or later in life remains unclear.

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