Pulsatile Cortisol Feedback on ACTH Secretion Is Mediated by the Glucocorticoid Receptor and Modulated by Gender
Author(s) -
Ferdinand Roelfsema,
Paul Aoun,
Johannes D. Veldhuis
Publication year - 2016
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2016-2405
Subject(s) - endocrinology , medicine , mifepristone , vasopressin , glucocorticoid , mineralocorticoid receptor , antiglucocorticoid , mineralocorticoid , glucocorticoid receptor , hydrocortisone , adrenocorticotropic hormone , secretagogue , aldosterone , receptor , hormone , biology , pregnancy , genetics
Factors that regulate physiological feedback by pulses of glucocorticoids on the hypothalamic-pituitary unit are sparsely defined in humans in relation to gluco- or mineralocorticoid receptor pathways, gender, age, and the sex steroid milieu.
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