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Clinical and Genetic Features of Patients With Type 2 Diabetes and Renal Glycosuria
Author(s) -
Siqian Gong,
Jiandong Guo,
Xueyao Han,
Meng Li,
Lingli Zhou,
Xiaoling Cai,
Yu Zhu,
Yingying Luo,
Simin Zhang,
Xianghai Zhou,
Yumin Ma,
Lig Ji
Publication year - 2017
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2016-2332
Subject(s) - glycosuria , medicine , diabetes mellitus , endocrinology , type 2 diabetes , urinary system , insulin resistance , type 2 diabetes mellitus
A sodium glucose cotransporter 2 (SGLT2) inhibitor, which increases urinary glucose excretion, was reported to decrease blood glucose levels and deaths among patients with type 2 diabetes mellitus (T2DM) and established cardiovascular disease. SLC5A2 and HNF1A mutations are associated with renal glycosuria, but their contributions to renal glycosuria in patients with T2DM are not well understood.

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