Incidence of Thyroid-Related Adverse Events in Melanoma Patients Treated With Pembrolizumab
Author(s) -
Jeroen de Filette,
Yanina Jansen,
Max Schreuer,
Hendrik Everaert,
Brigitte Velkeniers,
Bart Neyns,
Bert Bravenboer
Publication year - 2016
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2016-2300
Subject(s) - medicine , pembrolizumab , thyroid , thyroiditis , levothyroxine , thyroid function , anti thyroid autoantibodies , thyroid function tests , autoimmune thyroiditis , gastroenterology , autoantibody , endocrinology , cancer , immunology , antibody , immunotherapy
Immune checkpoint blockade is associated with endocrine-related adverse events. Thyroid dysfunction during pembrolizumab therapy, an anti-programmed cell death 1 (PD-1) receptor monoclonal antibody, remains to be fully characterized.
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