Open AccessIRAK1, a Target of miR-146b, Reduces Cell Aggressiveness of Human Papillary Thyroid Carcinoma
Author(s) -
ChenKai Chou,
ShunYu Chi,
Cai-Hua Huang,
FongFu Chou,
ChaoCheng Huang,
RueTsuan Liu,
HongYo Kang
Publication year - 2016
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2016-2276
Subject(s) - thyroid carcinoma , papillary carcinoma , medicine , cancer research , thyroid , oncology , pathology , endocrinology
MicroRNA (miR)-146b is overexpressed in papillary thyroid carcinoma (PTC) and is associated with extrathyroidal invasion, advanced tumor stage, and poor prognosis. However, the underlying mechanism of miR-146b in relation to its oncogenic behavior in PTC and its putative targets remain unknown.
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