Whole-Exome Sequencing Study of Thyrotropin-Secreting Pituitary Adenomas | Zendy

Santosh Sapkota | Zendy; Kazuhiko Horiguchi | Zendy; Masahiko Tosaka | Zendy; Syozo Yamada | Zendy; Masanobu Yamada | Zendy

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Whole-Exome Sequencing Study of Thyrotropin-Secreting Pituitary Adenomas

Author(s) -

Santosh Sapkota,

Kazuhiko Horiguchi,

Masahiko Tosaka,

Syozo Yamada,

Masanobu Yamada

Publication year - 2016

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2016-2261

Subject(s) - exome sequencing , sanger sequencing , exome , biology , genetics , loss of heterozygosity , germline mutation , single nucleotide polymorphism , snp array , candidate gene , context (archaeology) , copy number analysis , germline , carcinogenesis , copy number variation , mutation , cancer research , allele , gene , genotype , genome , paleontology

Thyrotropin (TSH)-secreting pituitary adenomas (TSHomas) are a rare cause of hyperthyroidism, and the genetic aberrations responsible remain unknown.

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