Identification of an AR Mutation-Negative Class of Androgen Insensitivity by Determining Endogenous AR Activity | Zendy

Nadine Hornig | Zendy; Martin Ukat | Zendy; H. U. Schweikert | Zendy; Olaf Hiort | Zendy; Ralf Werner | Zendy; Stenvert L. S. Drop | Zendy; Martine Cools | Zendy; I A Hughes | Zendy; Laura Audí | Zendy; S. Faisal Ahmed | Zendy; Jeta Demiri | Zendy; Pascal Rodens | Zendy; Lisa Worch | Zendy; G. R. Wehner | Zendy; Alexandra Kulle | Zendy; Désirée Dunstheimer | Zendy; Elke MüllerRoßberg | Zendy; Thomas Reinehr | Zendy; Ahmed T Hadidi | Zendy; Anne Katrin Eckstein | Zendy; Carolyn Horst | Zendy; C. Seif | Zendy; R. Siebert | Zendy; Ole Ammerpohl | Zendy; P.M. Holterhus | Zendy

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Identification of an AR Mutation-Negative Class of Androgen Insensitivity by Determining Endogenous AR Activity

Author(s) -

Nadine Hornig,

Martin Ukat,

H. U. Schweikert,

Olaf Hiort,

Ralf Werner,

Stenvert L. S. Drop,

Martine Cools,

I A Hughes,

Laura Audí,

S. Faisal Ahmed,

Jeta Demiri,

Pascal Rodens,

Lisa Worch,

G. R. Wehner,

Alexandra Kulle,

Désirée Dunstheimer,

Elke MüllerRoßberg,

Thomas Reinehr,

Ahmed T Hadidi,

Anne Katrin Eckstein,

Carolyn Horst,

C. Seif,

R. Siebert,

Ole Ammerpohl,

P.M. Holterhus

Publication year - 2016

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2016-1990

Subject(s) - androgen receptor , androgen insensitivity syndrome , androgen , biology , endocrinology , mutation , medicine , gene , genetics , cancer research , cancer , hormone , prostate cancer

Only approximately 85% of patients with a clinical diagnosis complete androgen insensitivity syndrome and less than 30% with partial androgen insensitivity syndrome can be explained by inactivating mutations in the androgen receptor (AR) gene.

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