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Positive Feedback Loops between NrCAM and Major Signaling Pathways Contribute to Thyroid Tumorigenesis
Author(s) -
Yanfang Zhang,
Fang Sui,
Jingjing Ma,
Xiaojuan Ren,
Haixia Guan,
Qi Yang,
Jing Shi,
Meiju Ji,
Bingyin Shi,
Yue Sun,
Peng Hou
Publication year - 2016
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2016-1677
Subject(s) - thyroid cancer , carcinogenesis , cancer research , biology , pi3k/akt/mtor pathway , signal transduction , anaplastic thyroid cancer , mapk/erk pathway , gene knockdown , thyroid , cancer , microbiology and biotechnology , endocrinology , cell culture , genetics
Although neuronal cell adhesion molecule (NrCAM) has been reported to be overexpressed in papillary thyroid cancer (PTCs), its role in this disease remains largely unclear.

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