Augmented Angiogenic Factors Expression via FP Signaling Pathways in Peritoneal Endometriosis | Zendy

Halima Rakhila | Zendy; Mahéra Al-Akoum | Zendy; Charles J. Doillon | Zendy; Nicolas LacroixPepin | Zendy; Mathieu Lebœuf | Zendy; Madeleine Lemyre | Zendy; Ali Akoum | Zendy; Marc Pouliot | Zendy

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Augmented Angiogenic Factors Expression via FP Signaling Pathways in Peritoneal Endometriosis

Author(s) -

Halima Rakhila,

Mahéra Al-Akoum,

Charles J. Doillon,

Nicolas LacroixPepin,

Mathieu Lebœuf,

Madeleine Lemyre,

Ali Akoum,

Marc Pouliot

Publication year - 2016

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2016-1569

Subject(s) - angiogenesis , stromal cell , prostanoid , endocrinology , vascular endothelial growth factor , medicine , cancer research , cxc chemokine receptors , vascular endothelial growth factor a , biology , receptor , microbiology and biotechnology , chemistry , prostaglandin , chemokine , chemokine receptor , vegf receptors

Angiogenesis is required for ectopic endometrial tissue growth. Our previous studies showed that prostaglandin F 2α (PGF 2α ) biosynthetic enzymes and receptor were markedly elevated in endometriotic lesions and that PGF 2α is a potent angiogenic factor in endothelial cells.

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