Open AccessDifferent Effects of Intraperitoneal and Subcutaneous Insulin Administration on the GH-IGF-1 Axis in Type 1 Diabetes
Author(s) -
Peter R. van Dijk,
S. J. J. Logtenberg,
Simona I. Chisalita,
Christina A. Hedman,
Klaas H. Groenier,
Rijk O. B. Gans,
Nanne Kleefstra,
Hans J. Arnqvist,
Henk J.G. Bilo
Publication year - 2016
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2016-1473
Subject(s) - liter , medicine , endocrinology , insulin , confidence interval , diabetes mellitus , type 1 diabetes
In type 1 diabetes mellitus, low levels of insulin-like growth factor -1 (IGF-1) and IGF binding protein-3 (IGFBP-3) and high levels of GH and IGFBP-1 are present, probably due to portal vein insulinopenia.
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