A Novel and Practical Screening Tool for the Detection of Silent Myocardial Infarction in Patients With Type 2 Diabetes
Author(s) -
Peter Swoboda,
Adam K McDiarmid,
Bara Erhayiem,
Philip Haaf,
Ananth Kidambi,
Graham Fent,
Laura E Dobson,
Tarique A Musa,
Pankaj Garg,
Graham Law,
Mark T. Kearney,
Julian H. Barth,
Ramzi Ajjan,
John P. Greenwood,
Sven Plein
Publication year - 2016
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2016-1318
Subject(s) - medicine , cardiology , asymptomatic , myocardial infarction , ejection fraction , type 2 diabetes , receiver operating characteristic , diabetes mellitus , natriuretic peptide , population , heart failure , environmental health , endocrinology
Silent myocardial infarction (MI) is a prevalent finding in patients with type 2 diabetes and is associated with significant mortality and morbidity. Late gadolinium enhancement (LGE) by cardiovascular magnetic resonance (CMR) is the most validated technique for detection of silent MI, but is time-consuming, costly, and requires administration of intravenous contrast. We therefore planned to develop a simple and low-cost population screening tool to identify those at highest risk of silent MI validated against the CMR reference standard.
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