Bone and Mineral Metabolism: Where Are We, Where Are We Going, and How Will We Get There?
Author(s) -
Henry M. Kronenberg
Publication year - 2016
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2015-3607
Subject(s) - human disease , hormone , human bone , bone mineral , biology , bone remodeling , disease , bioinformatics , computational biology , physiology , neuroscience , medicine , osteoporosis , pathology , genetics , endocrinology , in vitro
Advances in diagnosing and treating metabolic bone diseases will require ways to assess cellular signaling within human bones, ideally noninvasively. Only then will we be able to fully harness the increased molecular understanding of bone that derives from human genetics and model organisms, primarily rodents. New hormones regulating mineral ion homeostasis surely remain to be discovered, probably through advances in the study of human genetic disease.
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