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Compensatory increases in fibroblast growth factor 23 (FGF23) with increasing phosphate intake may adversely impact health. However, population and clinical studies examining the link between phosphate intake and FGF23 levels have focused mainly on populations living in highly industrialized societies in which phosphate exposure may be homogenous.

Fibroblast Growth Factor-23 (FGF-23) Levels Differ Across Populations by Degree of Industrialization