The Etiology and Clinical Features of Non-CAH Gonadotropin-Independent Precocious Puberty: A Multicenter Study | Zendy

Zeynep Atay | Zendy; Ediz Yeşilkaya | Zendy; Şenay Savaş Erdeve | Zendy; Serap Turan | Zendy; Leyla Akın | Zendy; Erdal Eren | Zendy; Esra Döğer | Zendy; Zehra Aycan | Zendy; Zehra Yavaş Abalı | Zendy; Ayşehan Akıncı | Zendy; Zeynep Şıklar | Zendy; Samim Özen | Zendy; Cengiz Kara | Zendy; Meltem Tayfun | Zendy; Erkan Sarı | Zendy; Filiz Tütüncüler | Zendy; Gülcan Seymen Karabulut | Zendy; Gülay Karagüzel | Zendy; Semra Çeti̇nkaya | Zendy; Halil Sağlam | Zendy; Aysun Bıdecı | Zendy; Selim Kurtoğlu | Zendy; Tülay Güran | Zendy; Abdullah Bereket | Zendy

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The Etiology and Clinical Features of Non-CAH Gonadotropin-Independent Precocious Puberty: A Multicenter Study

Author(s) -

Zeynep Atay,

Ediz Yeşilkaya,

Şenay Savaş Erdeve,

Serap Turan,

Leyla Akın,

Erdal Eren,

Esra Döğer,

Zehra Aycan,

Zehra Yavaş Abalı,

Ayşehan Akıncı,

Zeynep Şıklar,

Samim Özen,

Cengiz Kara,

Meltem Tayfun,

Erkan Sarı,

Filiz Tütüncüler,

Gülcan Seymen Karabulut,

Gülay Karagüzel,

Semra Çeti̇nkaya,

Halil Sağlam,

Aysun Bıdecı,

Selim Kurtoğlu,

Tülay Güran,

Abdullah Bereket

Publication year - 2016

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2015-3500

Subject(s) - etiology , medicine , precocious puberty , germ cell tumors , human chorionic gonadotropin , population , cohort , pediatrics , pathology , endocrinology , hormone , chemotherapy , environmental health

The causes of gonadotropin-independent precocious puberty are diverse, and often have overlapping clinical and biochemical features. With the exception of congenital adrenal hyperplasia (CAH), disorders that cause gonadotropin-independent precocious puberty (GIPP) are uncommon. The literature is devoid of any large-scale studies on the etiologic distribution of GIPP. The aim of this study was to determine the frequency of each etiology in a cohort of patients with GIPP (excluding those with CAH), and to evaluate the clinical and laboratory features of these patients.

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