Open AccessAsfotase Alfa Treatment Improves Survival for Perinatal and Infantile Hypophosphatasia
Author(s) -
Michael P. Whyte,
Cheryl R. Greenberg,
Keiichi Ozono,
Richard J. Riese,
Scott Moseley,
Agustin Melian,
David D. Thompson,
Nicholas Bishop,
Christine Hofmann
Publication year - 2015
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2015-3462
Subject(s) - hypophosphatasia , pediatrics , medicine , alkaline phosphatase , chemistry , biochemistry , enzyme
Hypophosphatasia (HPP) is an inborn error of metabolism that, in its most severe perinatal and infantile forms, results in 50-100% mortality, typically from respiratory complications.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom