Insulin Enhances Endothelial Function Throughout the Arterial Tree in Healthy But Not Metabolic Syndrome Subjects
Author(s) -
Linda A. Jahn,
LEE HARTLINE,
Nagashree Rao,
Brent R. Logan,
Justin J. Kim,
Kevin W. Aylor,
LiMing Gan,
Helena U. Westergren,
Eugene J. Barrett
Publication year - 2016
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2015-3293
Subject(s) - medicine , insulin resistance , hyperinsulinemia , arterial stiffness , endocrinology , pulse wave velocity , metabolic syndrome , brachial artery , endothelial dysfunction , insulin , postprandial , cardiology , blood pressure , obesity
Insulin reportedly impairs endothelial function in conduit arteries but improves it in resistance and microvascular arterioles in healthy humans. No studies have assessed endothelial function at three arterial levels in healthy or metabolic syndrome (METSYN) subjects.
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