Glucose-Dependent Insulinotropic Polypeptide Is Associated With Lower Low-Density Lipoprotein But Unhealthy Fat Distribution, Independent of Insulin: The ADDITION-PRO Study
Author(s) -
Cathrine Laustrup Møller,
Dorte Vistisen,
Kristine Færch,
Nanna B. Johansen,
Daniel R. Witte,
Anna Jonsson,
Oluf Pedersen,
Torben Hansen,
Torsten Lauritzen,
Marit E. Jørgensen,
Signe S. Torekov,
Jens J. Holst
Publication year - 2015
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2015-3133
Subject(s) - medicine , endocrinology , insulin , type 2 diabetes , gastric inhibitory polypeptide , lipoprotein , obesity , insulin resistance , lipid metabolism , abdominal obesity , diabetes mellitus , cholesterol , chemistry , waist , glucagon
Glucose-dependent insulinotropic polypeptide (GIP) may increase lipid clearance by stimulating lipid uptake. However, given that GIP promotes release of insulin by the pancreas and insulin is anti-lipolytic, the effect may be indirect.
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