HoxA13 Regulates Phenotype Regionalization of Human Pregnant Myometrium | Zendy

Liangliang Liu | Zendy; Haolong Li | Zendy; Daryanaz Dargahi | Zendy; Oksana Shynlova | Zendy; Donna M. Slater | Zendy; Steven J.M. Jones | Zendy; Stephen J. Lye | Zendy; Xuesen Dong | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

HoxA13 Regulates Phenotype Regionalization of Human Pregnant Myometrium

Author(s) -

Liangliang Liu,

Haolong Li,

Daryanaz Dargahi,

Oksana Shynlova,

Donna M. Slater,

Steven J.M. Jones,

Stephen J. Lye,

Xuesen Dong

Publication year - 2015

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2015-2815

Subject(s) - biology , myometrium , medicine , transcriptome , endocrinology , fetus , pregnancy , microarray analysis techniques , gene expression , andrology , gene , uterus , genetics

Bipedalism separates humans from most other animal species, but results in significant physiologic challenges, particularly with respect to the maintenance of pregnancy and induction of parturition. A contracted lower uterine segment (LUS) and a relaxed uterine fundal myometrium (FUN) during pregnancy are required to prevent pressure on the cervix from the fetal head due to gravity. With the onset of labor, this regionalization of myometrial function must be reversed, allowing descent of the fetus, dilation of the cervix, and expulsion of the fetus through the birth canal. However, the molecular mechanisms remain unclear.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research