Implications of Androgen Assay Accuracy in the Phenotyping of Women With Polycystic Ovary Syndrome | Zendy

Flavia Tosi | Zendy; Tom Fiers | Zendy; JeanMarc Kaufman | Zendy; Marlene Dall'Alda | Zendy; Rossella Moretta | Zendy; Vito Angelo Giagulli | Zendy; Enzo Bonora | Zendy; Paolo Moghetti | Zendy

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Implications of Androgen Assay Accuracy in the Phenotyping of Women With Polycystic Ovary Syndrome

Author(s) -

Flavia Tosi,

Tom Fiers,

JeanMarc Kaufman,

Marlene Dall'Alda,

Rossella Moretta,

Vito Angelo Giagulli,

Enzo Bonora,

Paolo Moghetti

Publication year - 2015

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2015-2807

Subject(s) - polycystic ovary , hyperandrogenism , androstenedione , gold standard (test) , medicine , androgen , androgen excess , hirsutism , endocrinology , gynecology , hormone , obesity , insulin resistance

Hyperandrogenism is a common feature of women with polycystic ovary syndrome (PCOS) and is considered a cardinal element for the diagnosis and phenotyping of this condition. Unfortunately, routinely available methods for measuring serum androgens suffer from major limitations. No data are available on the impact of androgen assay quality on the assignment of PCOS women to the different clinical phenotypes of PCOS, when defined according to the Rotterdam criteria for diagnosis.

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