Diurnal Cortisol Rhythm Is Associated With Adverse Cardiac Events and Mortality in Coronary Artery Bypass Patients | Zendy

Amy Ronaldson | Zendy; Tara Kidd | Zendy; Lydia Poole | Zendy; Elizabeth Leigh | Zendy; Marjan Jahangiri | Zendy; Andrew Steptoe | Zendy

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Diurnal Cortisol Rhythm Is Associated With Adverse Cardiac Events and Mortality in Coronary Artery Bypass Patients

Author(s) -

Amy Ronaldson,

Tara Kidd,

Lydia Poole,

Elizabeth Leigh,

Marjan Jahangiri,

Andrew Steptoe

Publication year - 2015

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2015-2617

Subject(s) - medicine , cardiology , rhythm , circadian rhythm , artery , adverse effect

There is growing evidence that the hypothalamic-pituitary-adrenal axis plays a role in the progression of cardiovascular disease. We examined the relationship between diurnal cortisol rhythm and adverse events in patients undergoing coronary artery bypass graft (CABG) surgery. We hypothesized that a flatter presurgical diurnal cortisol slope would be associated with higher rates of adverse cardiac events and death in the years following the CABG procedure.

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