A Case for Conservative Management: Characterizing the Natural History of Radiographically Diagnosed Rathke Cleft Cysts | Zendy

Silas A Culver | Zendy; Yuval Grober | Zendy; David A. Ornan | Zendy; James T. Patrie | Zendy; Edward H. Oldfield | Zendy; John A. Jane | Zendy; Michael O. Thorner | Zendy

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A Case for Conservative Management: Characterizing the Natural History of Radiographically Diagnosed Rathke Cleft Cysts

Author(s) -

Silas A Culver,

Yuval Grober,

David A. Ornan,

James T. Patrie,

Edward H. Oldfield,

John A. Jane,

Michael O. Thorner

Publication year - 2015

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2015-2604

Subject(s) - medicine , asymptomatic , natural history , conservative management , cyst , magnetic resonance imaging , retrospective cohort study , radiology , population , surgery , environmental health

Rathke cleft cysts (RCCs) are benign embryonic remnants of the Rathke's pouch found in 13% to 33% of the general population. When symptomatic, they manifest themselves by compressing adjacent structures, causing pressure effects such as headache, visual disturbance, or pituitary hormone deficits. Most RCCs are asymptomatic, and their management remains controversial. Surgical resection has generally been indicated to treat symptomatic RCCs but carries the risk of complications.

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