Human Chorionic Gonadotropin Partially Mediates Phthalate Association With Male and Female Anogenital Distance
Author(s) -
Jennifer J. Adibi,
Myoung Keun Lee,
Ashley I. Naimi,
Emily S. Barrett,
Ruby H.N. Nguyen,
Sheela Sathyanarayana,
Yaqi Zhao,
Mari-Paule Thiet,
J. Bruce Redmon,
Shanna H. Swan
Publication year - 2015
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2015-2370
Subject(s) - anogenital distance , phthalate , human chorionic gonadotropin , sex organ , endocrinology , medicine , pregnancy , physiology , gonadotropin , gynecology , hormone , fetus , biology , chemistry , in utero , genetics , organic chemistry
Prenatal exposure to phthalates disrupts male sex development in rodents. In humans, the placental glycoprotein hormone human chorionic gonadotropin (hCG) is required for male development, and may be a target of phthalate exposure.
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