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Prokineticin Ligands and Receptors Are Expressed in the Human Fetal Ovary and Regulate Germ Cell Expression ofCOX2
Author(s) -
Sharon L. Eddie,
Andrew J. Childs,
Hazel L. Kinnell,
Pamela Brown,
Henry N. Jabbour,
Richard A. Anderson
Publication year - 2015
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2015-2330
Subject(s) - biology , ovary , medicine , endocrinology , germ cell , receptor , granulosa cell , folliculogenesis , fetus , microbiology and biotechnology , embryogenesis , embryo , pregnancy , genetics , gene
Fetal ovarian development and primordial follicle formation underpin future female fertility. Prokineticin (PROK) ligands regulate cell survival, proliferation, and angiogenesis in adult reproductive tissues including the ovary. However, their expression and function during fetal ovarian development remains unclear.

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