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Acute Sleep Loss Induces Tissue-Specific Epigenetic and Transcriptional Alterations to Circadian Clock Genes in Men
Author(s) -
Jonathan Cedernaes,
Megan E. Osler,
Sarah Voisin,
JanErik Broman,
Heike Vogel,
Suzanne L. Dickson,
Juleen R. Zierath,
Helgi B. Schiöth,
Christian Benedict
Publication year - 2015
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2015-2284
Subject(s) - clock , endocrinology , per1 , medicine , sleep deprivation , epigenetics , circadian rhythm , dna methylation , adipose tissue , biology , circadian clock , wakefulness , postprandial , gene expression , gene , genetics , diabetes mellitus , neuroscience , electroencephalography
Shift workers are at increased risk of metabolic morbidities. Clock genes are known to regulate metabolic processes in peripheral tissues, eg, glucose oxidation.

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