The Effect of Glucose on the Release and Bioactivity of Exosomes From First Trimester Trophoblast Cells
Author(s) -
Gregory E. Rice,
Katherin ScholzRomero,
Emma L. Sweeney,
Hassendrini N. Peiris,
Miharu Kobayashi,
Gregory Duncombe,
Murray D. Mitchell,
Carlos Salomón
Publication year - 2015
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2015-2270
Subject(s) - microvesicles , trophoblast , exosome , medicine , endocrinology , biology , umbilical vein , cytokine , microvesicle , placenta , andrology , in vitro , fetus , biochemistry , pregnancy , microrna , genetics , gene
Hyperglycemia and hypoxia are risk factors of metabolic complication during pregnancy. The interactions between oxygen and glucose-sensing pathways that regulate exosome bioactivity from placental cells, however, have not been established.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom