Hormonal, Radiological, NP-59 Scintigraphy, and Pathological Correlations in Patients With Cushing's Syndrome Due to Primary Pigmented Nodular Adrenocortical Disease (PPNAD)
Author(s) -
Delphine Vezzosi,
Florence Tenenbaum,
Laure Cazabat,
Frédérique Tissier,
Marie Bienvenu,
Carmen Carrasco,
M. Laloi–Michelin,
Gaëlle Barrande,
Hervé Lefèbvre,
S. Hiéronimus,
Antoine Tabarin,
Xavier Bertagna,
P. Legmann,
MarieChristine Vantyghem,
Jérôme Bertherat
Publication year - 2015
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2015-2174
Subject(s) - carney complex , pathological , medicine , scintigraphy , radiology , cushing syndrome , pathology , biology , biochemistry , gene
Primary pigmented nodular adrenocortical disease (PPNAD) is a rare cause of ACTH-independent Cushing's syndrome that may occur in an isolated form or as part of Carney complex. The diagnosis of this disease can be difficult preoperatively because computed tomography (CT) scan can be normal or suggest unilateral adrenal lesion, which can impede the correct diagnosis of bilateral adrenal disease.
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