Proportion of Undercarboxylated Osteocalcin and Serum P1NP Predict Incidence of Myocardial Infarction in Older Men
Author(s) -
Bu B. Yeap,
Helman Alfonso,
S. A. Paul Chubb,
Elizabeth Byrnes,
John Beilby,
Peter R. Ebeling,
Carolyn A Allan,
Carl Schultz,
Graeme J. Hankey,
Jonathan Golledge,
Leon Flicker,
Paul E. Norman
Publication year - 2015
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2015-1899
Subject(s) - medicine , osteocalcin , confidence interval , hazard ratio , myocardial infarction , incidence (geometry) , endocrinology , odds ratio , n terminal telopeptide , stroke (engine) , cardiology , biology , alkaline phosphatase , mechanical engineering , biochemistry , physics , optics , enzyme , engineering
Undercarboxylated osteocalcin (ucOC) modulates insulin secretion and sensitivity in mice, and higher ucOC is associated with lower prevalence of diabetes in men. The influence of ucOC distinct from other markers of bone turnover on incidence of cardiovascular events is unclear.
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