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Effect of Early Parenteral Nutrition on the HPA Axis and on Treatment With Corticosteroids in Intensive Care Patients
Author(s) -
Philippe Meersseman,
Eva Boonen,
Bram Peeters,
Sarah Vander Perre,
Pieter Wouters,
Lies Langouche,
Greet Van den Berghe
Publication year - 2015
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2015-1846
Subject(s) - medicine , septic shock , odds ratio , adrenal insufficiency , confidence interval , shock (circulatory) , hydrocortisone , incidence (geometry) , endocrinology , parenteral nutrition , gastroenterology , randomized controlled trial , sepsis , physics , optics
Nutrition can affect the hypothalamus-pituitary-adrenal axis. We hypothesized that early administration of parenteral nutrition (PN) during critical illness reduces plasma ACTH and cortisol concentrations and thereby increases the use of corticosteroids.

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