The Effect of Treatment With PTH on Undercarboxylated Osteocalcin and Energy Metabolism in Hypoparathyroidism
Author(s) -
Torben Harsløf,
Tanja Sikjær,
Lotte Sørensen,
Steen B. Pedersen,
Leif Mosekilde,
Bente Langdahl,
Lars Rejnmark
Publication year - 2015
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2015-1477
Subject(s) - endocrinology , medicine , osteocalcin , placebo , parathyroid hormone , bone remodeling , glucose homeostasis , carbohydrate metabolism , insulin resistance , hypoparathyroidism , insulin , biology , calcium , alkaline phosphatase , biochemistry , alternative medicine , pathology , enzyme
Undercarboxylated osteocalcin (ucOC) has been shown to affect glucose metabolism in mice. We recently randomized patients with hypoparathyroidism to treatment with PTH or placebo and demonstrated a marked increase in total osteocalcin.
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