Bone Material Strength as Measured by Microindentation In Vivo Is Decreased in Patients With Fragility Fractures Independently of Bone Mineral Density
Author(s) -
F. Malgo,
Neveen A. T. Hamdy,
Socrates E. Papapoulos,
Natasha M. AppelmanDijkstra
Publication year - 2015
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2014-4346
Subject(s) - osteopenia , medicine , bone mineral , osteoporosis , femoral neck , frax , fragility fracture , fragility , dentistry , densitometry , fracture (geology) , bone density , osteoporotic fracture , urology , materials science , chemistry , composite material
Bone mineral density (BMD) does not fully capture fracture risk as the majority of fractures occur in patients with osteopenia, suggesting that altered bone material properties and changes in microarchitecture may contribute to fracture risk.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom