High Postnatal Growth Hormone Levels Are Related to Cognitive Deficits in a Group of Children Born Very Preterm | Zendy

Shan E. Scratch | Zendy; Peter J. Anderson | Zendy; Lex W. Doyle | Zendy; Deanne K. Thompson | Zendy; Zohra M. Ahmadzai | Zendy; Ronda F. Greaves | Zendy; Terrie E. Inder | Zendy; Rod W. Hunt | Zendy

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High Postnatal Growth Hormone Levels Are Related to Cognitive Deficits in a Group of Children Born Very Preterm

Author(s) -

Shan E. Scratch,

Peter J. Anderson,

Lex W. Doyle,

Deanne K. Thompson,

Zohra M. Ahmadzai,

Ronda F. Greaves,

Terrie E. Inder,

Rod W. Hunt

Publication year - 2015

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2014-4342

Subject(s) - context (archaeology) , pediatrics , cognition , gestation , medicine , brain development , cognitive development , psychology , developmental psychology , pregnancy , neuroscience , psychiatry , biology , paleontology , genetics

Little is known regarding the influence of GH on brain development, especially in infants born very preterm (VP; <30 weeks' gestation). Preterm infants are thought to have higher levels of GH in the first days of life compared with full-term infants. VP infants experience cognitive difficulties in childhood and have a diffuse pattern of structural brain abnormalities. This study aimed to explore the relationship between postnatal GH concentrations following VP birth and its association with cognitive functioning and brain volumes at age 7 years.

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