RM-493, a Melanocortin-4 Receptor (MC4R) Agonist, Increases Resting Energy Expenditure in Obese Individuals | Zendy

Kong Y. Chen | Zendy; Ranganath Muniyappa | Zendy; Brent S. Abel | Zendy; Katherine Mullins | Zendy; Pamela Staker | Zendy; Robert J. Brychta | Zendy; Xiongce Zhao | Zendy; Michael Ring | Zendy; Tricia Psota | Zendy; Roger D. Cone | Zendy; Brandon L. Panaro | Zendy; Keith Gottesdiener | Zendy; Lex H.T. Van der Ploeg | Zendy; Marc L. Reitman | Zendy; Monica C. Skarulis | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

RM-493, a Melanocortin-4 Receptor (MC4R) Agonist, Increases Resting Energy Expenditure in Obese Individuals

Author(s) -

Kong Y. Chen,

Ranganath Muniyappa,

Brent S. Abel,

Katherine Mullins,

Pamela Staker,

Robert J. Brychta,

Xiongce Zhao,

Michael Ring,

Tricia Psota,

Roger D. Cone,

Brandon L. Panaro,

Keith Gottesdiener,

Lex H.T. Van der Ploeg,

Marc L. Reitman,

Monica C. Skarulis

Publication year - 2015

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2014-4024

Subject(s) - resting energy expenditure , crossover study , placebo , agonist , melanocortin 4 receptor , respiratory quotient , medicine , context (archaeology) , endocrinology , confidence interval , meal , body mass index , energy expenditure , zoology , melanocortin , receptor , biology , paleontology , alternative medicine , pathology

Activation of the melanocortin-4 receptor (MC4R) with the synthetic agonist RM-493 decreases body weight and increases energy expenditure (EE) in nonhuman primates. The effects of MC4R agonists on EE in humans have not been examined to date.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research