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Follicular Fluid Concentrations of Lipids and Their Metabolites Are Associated With Intraovarian Gonadotropin-Stimulated Androgen Production in Women Undergoing In Vitro Fertilization
Author(s) -
Alexandre Gervais,
M.-C. Battista,
Belina CarranzaMamane,
Hélène B. Lavoie,
Jean-Patrice Baillargeon
Publication year - 2015
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2014-3649
Subject(s) - follicular fluid , follicular phase , in vitro fertilisation , androgen , human fertilization , gonadotropin , medicine , endocrinology , in vitro , andrology , chemistry , biology , oocyte , biochemistry , microbiology and biotechnology , hormone , embryo , anatomy
Although growing evidence points toward a role of lipotoxicity in the development of hyperandrogenesis, the main feature of polycystic ovary syndrome, few studies directly assessed this association in vivo in humans, and none targeted the ovarian milieu.

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