Autoantibody Response Against NALP5/MATER in Primary Ovarian Insufficiency and in Autoimmune Addison's Disease
Author(s) -
Annalisa Brozzetti,
Mohammad Alimohammadi,
Silvia Morelli,
Viviana Minarelli,
Åsa Hallgren,
Roberta Giordano,
Annamaria De Bellis,
Roberto Perniola,
Olle Kämpe,
Alberto Falorni
Publication year - 2015
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2014-3571
Subject(s) - autoantibody , medicine , premature ovarian insufficiency , endocrinology , adrenal insufficiency , context (archaeology) , autoimmunity , autoimmune disease , immunology , hypoparathyroidism , antibody , disease , biology , paleontology
NACHT leucine-rich-repeat protein 5 (NALP5)/maternal antigen that embryo requires (MATER) is an autoantigen in hypoparathyroidism associated with autoimmune polyendocrine syndrome type 1 (APS1) but is also expressed in the ovary. Mater is an autoantigen in experimental autoimmune oophoritis.
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