Identification of a Hashimoto Thyroiditis Susceptibility Locus Via a Genome-wide Comparison With Graves' Disease
Author(s) -
Daisuke Oryoji,
Sho Ueda,
Ken Yamamoto,
Jaeduk Yoshimura Noh,
Ken Okamura,
Mitsuhiko Noda,
Natsuko Watanabe,
Ai Yoshihara,
Koichi Ito,
Takehiko Sasazuki
Publication year - 2014
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2014-3431
Subject(s) - odds ratio , single nucleotide polymorphism , genome wide association study , thyroiditis , snp , locus (genetics) , confidence interval , medicine , graves' disease , biology , genetic predisposition , genetics , genetic association , genotype , endocrinology , disease , gene
Hashimoto thyroiditis (HT) and Graves' disease (GD) share some immunological features. Determining the genetic basis that distinguishes HT from GD is key for a better understanding of the differences between these two related diseases.
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