Open AccessChanges in Anti-Thyroglobulin IgG Glycosylation Patterns in Hashimoto's Thyroiditis Patients
Author(s) -
Shanshan Yuan,
Qianqian Li,
Yang Zhang,
Chuncui Huang,
Hongmei Wu,
Yan Li,
Yalei Liu,
Nan Yu,
Hong Zhang,
Guizhi Lu,
Yanming Gao,
Ying Gao,
Xiaohui Guo
Publication year - 2014
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2014-2921
Subject(s) - thyroglobulin , thyroiditis , glycosylation , medicine , hashimoto disease , immunology , endocrinology , antibody , thyroid , biology , biochemistry
Sera of Hashimoto's thyroiditis (HT) patients are known to exhibit elevated levels of anti-thyroglobulin IgG (TgAb IgG). Therefore, TgAb IgG represents a hallmark of this debilitating autoimmune disease. The aim of our study was to investigate the differential expression of specific glycosylation patterns of TgAb IgG from HT patients and healthy blood donors.
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