Prolonged Pregnancy in Women Is Associated With Attenuated Myometrial Expression of Progesterone Receptor Co-Regulator Krüppel-Like Factor 9
Author(s) -
John Mark P. Pabona,
Daying Zhang,
David Ginsburg,
Frank A. Simmen,
Rosalia C. M. Simmen
Publication year - 2014
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2014-2846
Subject(s) - myometrium , endocrinology , medicine , mifepristone , chemokine , progesterone receptor , biology , receptor , pregnancy , uterus , cancer , estrogen receptor , breast cancer , genetics
Late-term pregnancy may lead to maternal and neonatal morbidity and mortality. Mice null for the progesterone receptor co-regulator Krüppel-like Factor 9 (KLF9) exhibit delayed parturition and increased incidence of neonatal deaths.
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